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SajjuSajju 
Hi,
I am trying to run 3D pharmacophore feature generation protocol but I am not sure how to write values in "Active properties" inside protocol. Every time when I run it shows that "Activity of compounds (list of compounds) is not greater than zero."

What is the format to write and how to solve this problem? Please let me know how to run this protocol.

Thnaks
Best Answer chosen by Sajju
TinaTina (Accelrys) 
Hi,
I understand, let me explain. You don’t type directly in the Activity Property field in the 3D QSAR protocol parameters.
If you open your input ligands .sd file in DS, you can enter the compound activity data into the Data table of the Molecule window.
To add a property column: right-click in the Data table and select ‘Add Attribute’ (see screenshot below), give a Name. For example, I call it my_activity. Click OK.

Then you’ll see a new column in the Data table called ‘my_activity’, and you can enter the activity values for each compound in that column.
And then when you click in the Activity Propery field in the protocol parameters, you can pick my_activity from the list. That’s all.
 
User-added image

In short, the Activity Property parameter is for the user to pick the name of the property containing the molecular activity data. The activity data should be in the input ligands SD file.
Hope this is clear.
 
Frank OellienFrank Oellien 
Dear Colleagues,

do you have plans to publish/provide also a new version of DS Visualizer 4.5?

Best regards,
Frank
Best Answer chosen by Patricia (Accelrys) 
WolfgangWolfgang (BIOVIA) 
Dear Frank,

version 4.5 of Discovery Studio Visualizer is now available from the BIOVIA website; please make sure to check the system requirements before the installation.

You can find a list of this and more free BIOVIA software in the Download section of our Customer Support Center.

Best regards,
                     Wolfgang